Structures of proteases for ubiqutin and ubiquitin-like modifiers
نویسندگان
چکیده
منابع مشابه
Ubiquitin-like modifiers.
UBLs (ubiquitin-like proteins) are a major class of eukaryotic post-translational modifiers. UBLs are attached to numerous cellular proteins and to other macromolecules, thereby regulating a wide array of cellular processes. In this chapter we highlight a subset of UBLs and describe their regulatory roles in the cell.
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The post-translational modification of proteins with ubiquitin (Ub) or ubiquitin-like (Ubl) modifiers is an important signal in the regulation of a variety of biological processes. The attachment of either a single Ub, a 76 amino acid polypeptide, or multiple Ub entities helps to control the targeting of substrates for degradation. Processes such as receptor internalization, trafficking to the ...
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[This corrects the article on p. 105 in vol. 7, PMID: 27379156.].
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ژورنال
عنوان ژورنال: BMB Reports
سال: 2008
ISSN: 1976-6696
DOI: 10.5483/bmbrep.2008.41.6.435